BIOPHARMANET-TEC has competences in the field of drug discovery, drug delivery, process chemistry, pharmacology, experimental medicines, biochemistry and molecular biology, and makes use of the proper equipment to carry out the tasks assigned. The laboratory instruments belonging to BIOPHARMANET-TEC are herein reported, along with information about their location, use and property. EQUIPMENTFUNCTIONLOCATIONSTOCKORIGINERESPONSIBLEpMDIFilling of pressured devices for inhalationBPN-TEC Tecnopolo di ParmaN/AComodatoBettiniInstrument for thermal analysis DSCStudy of solid-state characteristicsFood and Drug Department5872, 5671POR-FESRBettiniInstrument for thermal analysis TGAStudy of solid-state characteristicsFood and Drug Department28,29POR-FESRBettiniInstrument for dissolution of solid pharmaceuticalsTo determine the dissolution rate and the release of solid pharmaceuticalsFood and Drug Department16, 19POR-FESRBettiniDisaggregation instrumentMeasure of disaggregation time of tabletsFood and Drug Department64POR-FESRBettiniAnimal facility “Charles River”Structures for animal careFood and Drug Department20POR-FESRBarocelli PetroniniUltrasound bath 8510 BransonPowder solubilization in waterFood and Drug Department46ConferimentoBettiniBassinaTo cover solid pharmaceuticals with con lipidic and polymeric filmsFood and Drug Department76, 78POR-FESRBettiniAnalytical scalesAnalytical scalesBPN-TEC Tecnopolo di Parma100103POR-FESRBettiniLaminar flow fume hoodHandling of biological samplesFood and Drug Department21POR-FESRBarocelliCentrifugesPhase separationFood and Drug Department, BPN-TEC Tecnopolo di Parma42POR-FESRSanti BrunoFluorocytometer Guava® easyCyte 5Quantification of fluorescence of biological samples, cells and organic solutionsFood and Drug Department61POR-FESRBerniniComprimitrice STYL’One EvolutionProduction of tabletsFood and Drug Department68POR-FESRBettiniVertical refrigerator (-86 °C)Samples and cells cryoconservationFood and Drug Department22POR-FESRBerniniFast HPLC Agilent 1200 SeriesIdentification and quantification of organic moleculesFood and Drug Department7-10, 15 11-14, 23POR-FESRBettiniDiffractometer instrument RigakuEvaluation of samples crystal structureFood and Drug Department6219ConferimentoBettiniLaser Diffractometer Malvern SprayTecDetermination of size and dimensional distribution of a powder or suspensionFood and Drug Department4-6POR-FESRBettiniCompact density determining instrumentMeasure of compact densityFood and Drug Department68POR-FESRBettiniDynamic Light Scattering (DLS)Determination of the size and superficial charge of a colloidal dispersionFood and Drug Department152712ConferimentoBettiniDynamic vapour sorption (DVS)Gravimetric analysisFood and Drug Department100003ConferimentoBettiniFermentator 10LProduction of peptides and proteins through microorganism fermentationBPN-TEC Tecnopolo di ParmaTBAConferimentoBrunoFriabilometerEvaluation of tablets friabilityFood and Drug Department63POR-FESRBettiniGranulator/MixerSmall scale production of mixture of various sizeBPN-TEC Tecnopolo di Parma74, 75POR-FESRBettiniCO2 thermostatic incubatorTo promote cellular growthFood and Drug Department30POR-FESRBerniniImpactators (ACI, NGI, Critical Flow Controller and 3 pumps)Evaluation of the aerodynamic characteristics of aerosolsFood and Drug Department31, 33, 6294, 4676, 100019ConferimentoBettiniLyophilizer Christ Alpha 2-4 LSC PlusProduction of solid pharmaceuticalsBPN-TEC Tecnopolo di Parma66POR-FESRBettiniTridimentional dynamic powder mixerFor powder mixing with a 3D movementBPN-TEC Tecnopolo di Parma158274ConferimentoBettiniRefrigerated microcentrifuge HermleIsolation of cellsFood and Drug Department37ConferimentoBarocelliFluid jet micronizer millTo mix active ingredients and excipients of small size (<10 uM)BPN-TEC Tecnopolo di ParmaN/AComodatoBettiniFluid bed granulation machine MiniGlattProduction of granulates of various sizeBPN-TEC Tecnopolo di Parma6312ConferimentoBettiniMini Spray DryerSpray drier for the production of microparticlesFood and Drug Department43,44POR-FESRBettiniHigh pressure homogenizerHomogenizer for emulsion, suspension and cells.BPN-TEC Tecnopolo di ParmaTBAConferimentoBrunoCapsule filling machinePrototype for the filling of hard gel capsulesBPN-TEC Tecnopolo di ParmaN/AComodatoBettiniHelium PycnometerMeasurement of powder densityFood and Drug Department100018ConferimentoBettiniReal-Time PCR System StepOneDNA amplification and quantificationMedicine Department69POR-FESRPetroniniRotogranulatorPreparation of powder and granulates mixturesBPN-TEC Tecnopolo di Parma6903ConferimentoBettiniUV-Vis floe cell spectrophotometer Perkin ElmerDetermination of the dissolution process of a solid pharmaceuticalFood and Drug Department6462ConferimentoBettiniLC MS/MS QTRAP4000Identification and quantification of various substancesFood and Drug Department70-81POR-FESRElviriMass spectrometer TSQ Quantum Access Max System with HESI ProbeHigh resolution mass chromatographer for the characterization of molecules of interestFood and Drug Department24-26POR-FESRMorTitrator Karl Fisher Mettler ToledoDetermination of water in a sampleFood and Drug Department32ConferimentoBettiniDigital rotational viscometerMeasurement of viscosity of small samplesFood and Drug Department45POR-FESRBettini
