BIOPHARMANET-TEC has competences in the field of drug discovery, drug delivery, process chemistry, pharmacology, experimental medicines, biochemistry and molecular biology, and makes use of the proper equipment to carry out the tasks assigned.
The laboratory instruments belonging to BIOPHARMANET-TEC are herein reported, along with information about their location, use and property.
EQUIPMENT | FUNCTION | LOCATION | STOCK | ORIGINE | RESPONSIBLE |
pMDI | Filling of pressured devices for inhalation | BPN-TEC Tecnopolo di Parma | N/A | Comodato | Bettini |
Instrument for thermal analysis DSC | Study of solid-state characteristics | Food and Drug Department | 5872, 5671 | POR-FESR | Bettini |
Instrument for thermal analysis TGA | Study of solid-state characteristics | Food and Drug Department | 28,29 | POR-FESR | Bettini |
Instrument for dissolution of solid pharmaceuticals | To determine the dissolution rate and the release of solid pharmaceuticals | Food and Drug Department | 16, 19 | POR-FESR | Bettini |
Disaggregation instrument | Measure of disaggregation time of tablets | Food and Drug Department | 64 | POR-FESR | Bettini |
Animal facility “Charles River” | Structures for animal care | Food and Drug Department | 20 | POR-FESR | Barocelli Petronini |
Ultrasound bath 8510 Branson | Powder solubilization in water | Food and Drug Department | 46 | Conferimento | Bettini |
Bassina | To cover solid pharmaceuticals with con lipidic and polymeric films | Food and Drug Department | 76, 78 | POR-FESR | Bettini |
Analytical scales | Analytical scales | BPN-TEC Tecnopolo di Parma | 100103 | POR-FESR | Bettini |
Laminar flow fume hood | Handling of biological samples | Food and Drug Department | 21 | POR-FESR | Barocelli |
Centrifuges | Phase separation | Food and Drug Department, BPN-TEC Tecnopolo di Parma | 42 | POR-FESR | Santi Bruno |
Fluorocytometer Guava® easyCyte 5 | Quantification of fluorescence of biological samples, cells and organic solutions | Food and Drug Department | 61 | POR-FESR | Bernini |
Comprimitrice STYL’One Evolution | Production of tablets | Food and Drug Department | 68 | POR-FESR | Bettini |
Vertical refrigerator (-86 °C) | Samples and cells cryoconservation | Food and Drug Department | 22 | POR-FESR | Bernini |
Fast HPLC Agilent 1200 Series | Identification and quantification of organic molecules | Food and Drug Department | 7-10, 15 11-14, 23 | POR-FESR | Bettini |
Diffractometer instrument Rigaku | Evaluation of samples crystal structure | Food and Drug Department | 6219 | Conferimento | Bettini |
Laser Diffractometer Malvern SprayTec | Determination of size and dimensional distribution of a powder or suspension | Food and Drug Department | 4-6 | POR-FESR | Bettini |
Compact density determining instrument | Measure of compact density | Food and Drug Department | 68 | POR-FESR | Bettini |
Dynamic Light Scattering (DLS) | Determination of the size and superficial charge of a colloidal dispersion | Food and Drug Department | 152712 | Conferimento | Bettini |
Dynamic vapour sorption (DVS) | Gravimetric analysis | Food and Drug Department | 100003 | Conferimento | Bettini |
Fermentator 10L | Production of peptides and proteins through microorganism fermentation | BPN-TEC Tecnopolo di Parma | TBA | Conferimento | Bruno |
Friabilometer | Evaluation of tablets friability | Food and Drug Department | 63 | POR-FESR | Bettini |
Granulator/Mixer | Small scale production of mixture of various size | BPN-TEC Tecnopolo di Parma | 74, 75 | POR-FESR | Bettini |
CO2 thermostatic incubator | To promote cellular growth | Food and Drug Department | 30 | POR-FESR | Bernini |
Impactators (ACI, NGI, Critical Flow Controller and 3 pumps) | Evaluation of the aerodynamic characteristics of aerosols | Food and Drug Department | 31, 33, 6294, 4676, 100019 | Conferimento | Bettini |
Lyophilizer Christ Alpha 2-4 LSC Plus | Production of solid pharmaceuticals | BPN-TEC Tecnopolo di Parma | 66 | POR-FESR | Bettini |
Tridimentional dynamic powder mixer | For powder mixing with a 3D movement | BPN-TEC Tecnopolo di Parma | 158274 | Conferimento | Bettini |
Refrigerated microcentrifuge Hermle | Isolation of cells | Food and Drug Department | 37 | Conferimento | Barocelli |
Fluid jet micronizer mill | To mix active ingredients and excipients of small size (<10 uM) | BPN-TEC Tecnopolo di Parma | N/A | Comodato | Bettini |
Fluid bed granulation machine MiniGlatt | Production of granulates of various size | BPN-TEC Tecnopolo di Parma | 6312 | Conferimento | Bettini |
Mini Spray Dryer | Spray drier for the production of microparticles | Food and Drug Department | 43,44 | POR-FESR | Bettini |
High pressure homogenizer | Homogenizer for emulsion, suspension and cells. | BPN-TEC Tecnopolo di Parma | TBA | Conferimento | Bruno |
Capsule filling machine | Prototype for the filling of hard gel capsules | BPN-TEC Tecnopolo di Parma | N/A | Comodato | Bettini |
Helium Pycnometer | Measurement of powder density | Food and Drug Department | 100018 | Conferimento | Bettini |
Real-Time PCR System StepOne | DNA amplification and quantification | Medicine Department | 69 | POR-FESR | Petronini |
Rotogranulator | Preparation of powder and granulates mixtures | BPN-TEC Tecnopolo di Parma | 6903 | Conferimento | Bettini |
UV-Vis floe cell spectrophotometer Perkin Elmer | Determination of the dissolution process of a solid pharmaceutical | Food and Drug Department | 6462 | Conferimento | Bettini |
LC MS/MS QTRAP4000 | Identification and quantification of various substances | Food and Drug Department | 70-81 | POR-FESR | Elviri |
Mass spectrometer TSQ Quantum Access Max System with HESI Probe | High resolution mass chromatographer for the characterization of molecules of interest | Food and Drug Department | 24-26 | POR-FESR | Mor |
Titrator Karl Fisher Mettler Toledo | Determination of water in a sample | Food and Drug Department | 32 | Conferimento | Bettini |
Digital rotational viscometer | Measurement of viscosity of small samples | Food and Drug Department | 45 | POR-FESR | Bettini |