Di seguito è riportata una lista non esaustiva delle pubblicazioni più significative svolte da ciascuna UP nell’ambito di attività del centro negli ultimi due anni U.O. BIOLOGIA CELLULARE dei TUMORI e IMMUNOTERAPIA A Novel Homozygous YARS2 Mutation in Two Italian Siblings and a Review of Literature. Ardissone A, Lamantea E, Quartararo J, Dallabona C, Carrara F, Moroni I, Donnini C, Garavaglia B, Zeviani M, Uziel G. JIMD Rep. 2015;20:95-101. doi: 10.1007/8904_2014_397. Epub 2015 Feb 1. http://www.ncbi.nlm.nih.gov/pubmed/25638461 CD38 and bone marrow microenvironment. Chillemi A, Zaccarello G, Quarona V, Lazzaretti M, Martella E, Giuliani N, Ferracini R, Pistoia V, Horenstein AL, Malavasi F. Front Biosci (Landmark Ed). 2014 Jan 1;19:152-62. http://www.ncbi.nlm.nih.gov/pubmed/24389178 EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia. Boczonadi V, Müller JS, Pyle A, Munkley J, Dor T, Quartararo J, Ferrero I, Karcagi V, Giunta M, Polvikoski T, Birchall D, Princzinger A, Cinnamon Y, Lützkendorf S, Piko H, Reza M, Florez L, Santibanez-Koref M, Griffin H, Schuelke M, Elpeleg O, Kalaydjieva L, Lochmüller H, Elliott DJ, Chinnery PF, Edvardson S, Horvath R. Nat Commun. 2014 Jul 3;5:4287. doi: 10.1038/ncomms5287. http://www.ncbi.nlm.nih.gov/pubmed/24989451 Microcirculation density and maturity in uterine and soft tissue leiomyosarcomas: an immunohistochemical study. Caraffi S, Corradi D, Campanini N, Govoni P, Rocchi L, Perris R, Mangieri D. Histol Histopathol. 2015 Jan;30(1):69-76. Epub 2014 Jul 21. http://www.ncbi.nlm.nih.gov/pubmed/25046102 MMPs and angiogenesis affect the metastatic potential of a human vulvar leiomyosarcoma cell line. Alias C, Rocchi L, Ribatti D, Caraffi S, D’Angelo A, Perris R, Mangieri D. J Cell Mol Med. 2015 May 22. doi: 10.1111/jcmm.12565. http://www.ncbi.nlm.nih.gov/pubmed/26010680 p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative p53 expression. Novello C, Pazzaglia L, Conti A, Quattrini I, Pollino S, Perego P, Picci P, Benassi MS. PLoS One. 2014 Dec 9;9(12):e114757. doi: 10.1371/journal.pone.0114757. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/25490093 Prognostic role of nuclear factor/IB and bone remodeling proteins in metastatic giant cell tumor of bone: A retrospective study. Quattrini I, Pollino S, Pazzaglia L, Conti A, Novello C, Ferrari C, Pignotti E, Picci P, Benassi MS. J Orthop Res. 2015 Mar 12. doi: 10.1002/jor.22873 http://www.ncbi.nlm.nih.gov/pubmed/25764026 Proteoglycan-based diversification of disease outcome in head and neck cancer patients identifies NG2/CSPG4 and syndecan-2 as unique relapse and overall survival predicting factors. Farnedi A, Rossi S, Bertani N, Gulli M, Silini EM, Mucignat MT, Poli T, Sesenna E, Lanfranco D, Montebugnoli L, Leonardi E, Marchetti C, Cocchi R, Ambrosini-Spaltro A, Foschini MP, Perris R. BMC Cancer. 2015 May 3;15(1):352. doi: 10.1186/s12885-015-1336-4. http://www.ncbi.nlm.nih.gov/pubmed/25935541 The angiogenic asset of soft tissue sarcomas: a new tool to discover new therapeutic targets. Rocchi L, Caraffi S, Perris R, Mangieri D. Biosci Rep. 2014 Nov 4;34(6):e00147. doi: 10.1042/BSR20140075. http://www.ncbi.nlm.nih.gov/pubmed/25236925 Theranostic impact of NG2/CSPG4 proteoglycan in cancer. Nicolosi PA, Dallatomasina A, Perris R. Theranostics. 2015 Feb 15;5(5):530-44. doi: 10.7150/thno.10824. eCollection 2015. Review http://www.ncbi.nlm.nih.gov/pubmed/25767619 U.O. PATOLOGIA GENERALE Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease Bianchi MG, Bardelli D, Chiu M, Bussolati O. Cell Mol Life Sci. 2014 Jun;71(11):2001-15. doi: 10.1007/s00018-013-1484-0. Epub 2013 Oct 26. Comprehensive In Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy. Farcal L, Torres Andón F, Di Cristo L, Rotoli BM, Bussolati O, Bergamaschi E, Mech A, Hartmann NB, Rasmussen K, Riego-Sintes J, Ponti J, Kinsner-Ovaskainen A, Rossi F, Oomen A, Bos P, Chen R, Bai R, Chen C, Rocks L, Fulton N, Ross B, Hutchison G, Tran L, Mues S, Ossig R, Schnekenburger J, Campagnolo L, Vecchione L, Pietroiusti A, Fadeel B. PLoS One. 2015 May 21;10(5):e0127174. doi: 10.1371/journal.pone.0127174. eCollection 2015. PMC4440714. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. Krokowski D, Jobava R, Guan BJ, Farabaugh K, Wu J, Majumder M, Bianchi MG, Snider MD, Bussolati O, Hatzoglou M. J Biol Chem. 2015 Jul 17;290(29):17822-37. doi: 10.1074/jbc.M114.636217. Epub 2015 Jun 3. Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts. Chiu M, Tardito S, Pillozzi S, Arcangeli A, Armento A, Uggeri J, Missale G, Bianchi MG, Barilli A, Dall’Asta V, Campanini N, Silini EM, Fuchs J, Armeanu-Ebinger S, Bussolati O. Br J Cancer. 2014 Sep 9;111(6):1159-67. doi: 10.1038/bjc.2014.425. Epub 2014 Jul 29 Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: a single-cell monitoring toxicity assay Rotoli BM, Gatti R, Movia D, Bianchi MG, Di Cristo L, Fenoglio I, Sonvico F, Bergamaschi E, Prina-Mello A, Bussolati O. Nanotoxicology. 2015 Mar;9(2):230-41. doi: 10.3109/17435390.2014.918203. Epub 2014 May 29. Imogolite: an aluminosilicate nanotube endowed with low cytotoxicity and genotoxicity. Rotoli BM, Guidi P, Bonelli B, Bernardeschi M, Bianchi MG, Esposito S, Frenzilli G, Lucchesi P, Nigro M, Scarcelli V, Tomatis M, Zanello PP, Fubini B, Bussolati O, Bergamaschi E. Chem Res Toxicol. 2014 Jul 21;27(7):1142-54. doi: 10.1021/tx500002d. Epub 2014 Jun 16. Oxidative stress induced by copper and iron complexes with 8-hydroxyquinoline derivatives causes paraptotic death of HeLa cancer cells Barilli A, Atzeri C, Bassanetti I, Ingoglia F, Dall’Asta V, Bussolati O, Maffini M, Mucchino C, Marchiò L. Mol Pharm. 2014 Apr 7;11(4):1151-63. doi: 10.1021/mp400592n. Epub 2014 Mar 12 The effect of laser therapy on the expression of osteocalcin and osteopontin after tooth extraction in rats treated with zoledronate and dexamethasone Mergoni G, Vescovi P, Sala R, Merigo E, Passerini P, Maestri R, Corradi D, Govoni P, Nammour S, Bianchi MG Support Care Canc 2015; in press. doi: 10.1007/s00520-015-2847-x. Epub 2015 Jul 21 Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway Bianchi MG, Allegri M, Costa AL, Blosi M, Gardini D, Del Pivo C, Prina-Mello A, Di Cristo A, Bussolati O*, Bergamaschi E. Toxicol Res. 2015; 4, 385-398. doi: 10.1039/C4TX00193A. Epub 2014 Dec 18 U.O. MICROBIOLOGIA e VIROLOGIA A Wickerhamomyces anomalus killer strain in the malaria vector Anopheles stephensi. Cappelli A, Ulissi U, Valzano M, Damiani C, Epis S, Gabrielli MG, Conti S, Polonelli L, Bandi C, Favia G, Ricci I. PLoS One. 2014 May 1; 9(5):e95988. doi: 10.1371/journal.pone.0095988. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/24788884 Anti-tumor activities of peptides corresponding to conserved complementary determining regions from different immunoglobulins. Figueiredo CR, Matsuo AL, Massaoka MH, Polonelli L, Travassos LR. Peptides. 2014 Jun 24. pii: S0196-9781(14)00180-6. doi: 10.1016/j.peptides.2014.06.007. [Epub ahead of print] Antimicrobial activity of poultry bone and meat trimmings hydrolyzates in low-sodium turkey food. Zanello PP, Sforza S, Dossena A, Lambertini F, Bottesini C, Nikolaev IV, Koroleva O, Ciociola T, Magliani W, Conti S, Polonelli L. Food Funct. 2014 Feb; 5(2):220-8. doi: 10.1039/c3fo60454c. http://www.ncbi.nlm.nih.gov/pubmed/24284558 In vitro and in vivo activity of a killer peptide against Malassezia pachydermatis causing otitis in dogs. Cafarchia C, Immediato D, Paola GD, Magliani W, Ciociola T, Conti S, Otranto D, Polonelli L. Med Mycol. 2014 May; 52(4):350-5. doi: 10.1093/mmy/myt016. http://www.ncbi.nlm.nih.gov/pubmed/24625672 Vaccination of heifers with anaflatoxin improves the reduction of aflatoxin b1 carry over in milk of lactating dairy cows. Giovati L, Gallo A, Masoero F, Cerioli C, Ciociola T, Conti S, Magliani W, Polonelli L. PLoS One. 2014 Apr 8; 9(4):e94440. doi: 10.1371/journal.pone.0094440. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/24714096
